background and objective: haemophilus influenzae type b (hib) is divided into two distinct genotypes, type i and type ii, based on the structure of capsular polysaccharides. the capsulation locus of haemophilus influenzae type b consists of three functionally distinct regions, designated regions 1 to 3. region iii contains hcsa and hcsb genes; however, notable sequence variation in this region ...

guillain barre syndrome (gbs) is an inflammatory, usually demyelinating, polyneuropathy; clinically characterized by acute onset of symmetric progressive muscle weakness with loss of myotatic reflexes. thirty five patients with gbs, defined clinically according to the criteria of asbury and cornblath, were recruited from three hospital affiliated to tehran university of medical sciences.as a co...

nonencapsulated, nontypeable hemophilus influenzae (nthi) remains an important cause of acute otitis and respiratory diseases in children and adults. nthi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. the bacteria can also cause chronic dise...

background: haemophilus influenzae type b (hib) has emerged as the predominant cause of meningitis in developing coun­tries wherever it has been studied using good microbiologic procedures, but data  regarding frequency, antimicrobial sus­ceptibility and preferable method for detection of haemophilus influenzae type b isolated from  iranian patients  were scarce. methods: one thousand and eight...

introduction : haemophilus influenzae type b (hib) is a gram negative bacterium and one of the causative agents of acute bacterial meningitis, especially in infants and children less than 5 years old. lipooligosaccharide (los), one of the virulence factors which plays an important role in pathogenesis of hib, has multiple applications in diagnosis and conjugate vaccines. in this study, los extr...

introduction : haemophilus influenzae is a gram-negative bacterium causing a variety of respiratory infections in developing countries, especially in children. nasopharynx carriers of h. influenzae are the prominent source and transitional vectors of invasive diseases. as very limited information on h. influenzae carriage rate in iran was available, an evaluation on prevalence of this bacterium...

background: nontypeable haemophilus influenzae (nthi) is a common cause of respiratory tract disease and initiates infection by colonization in nasopharynx. the haemophilus influenzae (h. influenzae) hap adhesin is an auto transporter protein that promotes initial interaction with human epithelial cells. hap protein contains a 110 kda internal passenger domain called “haps” and a 45 kda c-termi...

Previous genetic analysis of Haemophilus influenzae strains isolated from genital and neonatal infections identified a group of biotype IV that constitutes a cryptic genospecies only distantly related to H. influenzae and H. Haemolyticus. Small-subunit rRNA genes of two representative strains of this genital Haemophilus genospecies (strains 16N and 2406) were sequenced. The analysis indicated t...